Caffeine and Pentagastrin Stimulation of Human Gastric Secretion
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منابع مشابه
Basal and pentagastrin-stimulated gastric secretion in young horses.
Equine gastric secretion was studied using a gastric cannula model after fasting (basal) and pentagastrin infusion. Gastric secretory rate, pH, osmolality, and electrolyte concentrations and outputs were determined over a 5-h period. Dose-response tests estimated that the maximally effective intravenous dose of pentagastrin was between 3 and 6 micrograms.kg-1.h-1. Basal secretory rate was 278 +...
متن کاملThe stability of gastric acid secretion during prolonged pentagastrin stimulation in man.
Prolonged stimulation with pentagastrin in doses of 100 and 500 ng h-1 kg-1 was performed in nine healthy subjects. A plateau in gastric secretion was reached after 90 min with 100 ng h-1 kg-1 and 500 ng h-1 kg-1 resulted in a secretory plateau after 60 min. When the plateau was reached the acid secretion rate was constant for the rest of the study, that is 4 h after beginning the pentagastrin ...
متن کاملHistamine dependence of pentagastrin-stimulated gastric acid secretion in rats.
Does gastrin stimulate gastric acid secretion by direct action on oxyntic cells, by releasing histamine, or by being potentiated by histamine? Previous studies in the mouse pointed to gastrin-regulated histamine release. Guinea pig and rat are well known to vary in their sensitivity to histamine. Therefore, the effects of histamine and pentagastrin were compared quantitatively on isolated, lume...
متن کاملEffect of D-glucose injection into ventromedial and lateral nuclei of hypothalamus on pentagastrin-induced gastric secretion in rat
It has been shown that those factors which affect gastric acid secretion through the ventromedial and lateral nuclei of hypothalamus, can significantly alter centrally-mediated secretion. There is much evidence that glucose is among these factors that through a central mechanism can decrease induced acid secretion. It appears that this effect is mediated through glucose-sensitive neurons within...
متن کاملThe Histamine Content of Human Gastric Juice after Pentagastrin and Insulin Stimulation
The quantity of histamine entering gastric juice has been followed during standard intramuscular pentagastrin tests in 10 patients (six duodenal ulcer, one gastric ulcer and three nonulcer dyspepsia), and during standard insulin tests in three (all duodenal ulcer). Following pentagastrin, peak histamine output occurred from 0-15 min in six patients and from 15-30 min in two. Acid output peaks f...
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ژورنال
عنوان ژورنال: Gastroenterology
سال: 1971
ISSN: 0016-5085
DOI: 10.1016/s0016-5085(19)33493-6